Puhan10, arnulf langhammer11, inmaculada alfageme12, pere almagro, julio ancochea14. Introductionin a literature metaanalysis, we showed survival benefits for regimens including cisplatin hazard ratio hr 0. Respiratory department, general hospital, montfermeil leraincy. Etude eabpcocphg du college des pneumologues des hopitaux generaux characteristics and management of acute exacerbations of copd in hospital. Characteristics of 6,083 new cases of nsclc according to sex abstract. Mild asthma includes intermittent and persistent mild asthma according to the global initiative for asthma gina classification, and. Median followup for survivors was 49 months iqr 4651. Respiratory department, general hospital, compiegne, france. In the 90s, taxanes, paclitaxel and docetaxel, emerged as important drugs for the. Acknowledgements we would like to thank the following for their contribution to these clinical studies in alphabetical order, by country. Solid neoplasms can be directly responsible for organ failures at the time of diagnosis or relapse. Respiratory department, general hospital, mulhouse. We previously developed a score 2008 score, based on age, dyspnea grade at steady state and number of clinical signs of severity predicting inhospital mortality in patients with aecopd visiting emergency departments eds.
A simple algorithm for the identification of clinical copd phenotypes pierreregis burgel1,2, jeanlouis paillasseur3, wim janssens4, jacques piquet5, gerben ter riet6, judith garciaaymerich7, borja cosio 8, per bakke9, milo a. Hopitauxetcliniques a montfermeil 93370 en seinesaint. The management of such specific complications relies on urgent chemotherapy and eventual instrumental or surgical procedures, combined with advanced life support. Intensivists are regularly confronted with the question of gastrointestinal bleeding. Management by the intensivist of gastrointestinal bleeding. Evangelisches krankenhaus gottingen weende, abteilung fur pneumologie, bovendenlenglern. Highrisk patients following hospitalisation for an acute. Caracteristiques et prise en charge des exacerbations aigues. We previously developed a score 2008 score, based on age, dyspnea grade at steady state and number of clinical signs of severity predicting inhospital mortality in patients with aecopd visiting. Cisplatin is the main drug and it is usually combined with other drugs such as vindesine, vinblastine, mitomycin c, ifosfamide and, more recently, gemcitabine, vinorelbine, paclitaxel and docetaxel. Despite the progress seen in the last decade in diagnosis and treatment, lung cancer has still a bad prognosis and a substantial number of patients died within the weeks following diagnosis.
Parmi les pneumologues exercant a montfermeil dans le 93370. Adult patients who received urgent chemotherapy in the icu for organ failure related to solid neoplasms were included. Methods french pulmonologists from nonacademic hospitals completed questionnaires on. That benefit was mainly observed when etoposide alone or in combination with cisplatin was included in the chemotherapy regimens. This study gives us a view on the management of lung cancer in the general hospital, only. Service pneumologie groupe hospitalier intercommunal le. But older patients are less frequently treated than younger patients and receive lower doses of treatment due to. Impact of a prevention strategy targeted at vascularaccess care on incidence of infections acquired in intensive care.
Univariate analyses were performed to compare dead and alive patients. The introduction of active chemotherapy in the treatment of nonsmallcell lung cancer nsclc has allowed some improvement in the survival of metastatic stage iv disease 1, 2. To assess longterm mortality and predictive factors of death after hospital admission for aecopd. The objective of this study was to quantify early mortality in lung cancer, to identify patients who are at high risk of early decease, and to describe their management in a real world. Feasibility of bioengineered tracheal and bronchial. We previously developed a score 2008 score, based on age, dyspnea grade at steady state and number of clinical signs of severity predicting in hospital mortality in patients with aecopd visiting emergency departments eds. Cisplatin is considered to be the main active drug.
There were 2585 deaths 87% in the development cohort and 10 deaths 87% in the validation cohort. Hospital 630 west 168th street ph8 east, room 101 new york, ny, usa brodie. Methods french pulmonologists from nonacademic hospitals completed questionnaires on patient. We present recommendations for management by the intensivist of gastrointestinal bleeding in adults and children, developed with the.
Highrisk patients following hospitalisation for an acute exacerbation of copd jacques piquet1, jeanmichel chavaillon2, philippe david3, francis martin4, franc. We present recommendations for management by the intensivist of gastrointestinal bleeding in adults and children, developed with the grade. Eggimann p, harbarth s, constantin mn, touveneau s, chevrolet jc and pittet d. No evidence of clinical efficacy of hydroxychloroquine in. Is the asthmatic patient competent to manage his disease. Groupe hospitalier intercommunal le raincy montfermeil. Proceedings of reanimation 2019, the french intensive care. Normandie university, unirouen, upres ea3830grhv, institute for research and innovation in. The european lung cancer working party elcwp designed a 3arm phase iii randomised trial to determine the role of accelerated chemotherapy in extensivedisease ed smallcell lung cancer sclc. Background realworld data describing management of patients with severe asthma are limited. Hospitalier intercommunal le raincy montfermeil, montfermeil, france.
Ghi le raincy montfermeil, 10 rue du general leclerc 93370 montfermeil, tel. Chemotherapy is the recommended treatment of advanced nonsmallcell lung cancer nsclc. Kbp2010cphg is a french prospective multicentre observational study. To date, the latest international recommendations regarding prevention and treatment for gastrointestinal bleeding lack a specific approach to the critically ill patients. This case series describes 90day mortality of patients who required tracheal, bronchial, or carinal reconstruction using stented aortic allografts supported by muscle flaps for treatment of inoperable airway disease including lung cancer, tracheal stenosis, or tracheomalacia. Carola, md senlis hospital france siog paris 2011, 5 november.
To address this issue, we conducted fasecphg france asthme severe college des pneumologues des hopitaux generaux, a descriptive, multicentric, and observational crosssectional study. The use of a severity score to help orientation decisions could improve the efficiency of care for acute exacerbations of copd aecopd. The authors would like to thank all the members of the steering committee and all the lung specialists who have actively participated in this study. This study uses a large dataset 7,051 included patients, about 20 % of all lung cancers diagnosed in france in 2010 and gives a true reflect of the lung cancer early mortality in a realworld in france in 2010. The copd diagnosis was established by a senior lung specialist. The zero risk concept for hospitalacquired infections. Details on study design and collected data have been published previously 9,10. Frontiers a phase iii randomized study comparing a. Mild asthma includes intermittent and persistent mild asthma according to the global initiative for asthma gina classification, and affects between 50% and 75% of asthmatic patients. Clinique pneumologie rive sud 2944, boul taschereau. The modalities of chemotherapy, requirements of adjuvant instrumental or surgical procedures, and organ.
A simple algorithm for the identification of clinical copd. Management by the intensivist of gastrointestinal bleeding in. A threearm phase iii randomised trial assessing, in. Au 10 rue du general leclerc, le pneumologue, dany goldgrantoledano, exerce au sein du ghi le raincy montfermeil dans le 93370. In the 90s, taxanes, paclitaxel and docetaxel, emerged. Eabpcocphg study by the college of general hospital respiratory physicians. The study protocol was approved by the advisory committee on research information processing in the health field cctirs on 19 november 2009 and the french information technology and freedoms commission cnil on 11 january 2010 909479. Chemotherapy efficiency and tolerance seem to be the same in younger and older age group in published studies. Puhan10, arnulf langhammer11, inmaculada alfageme12, pere almagro, julio ancochea14, bartolome r. Reduction of hospital utilization in patients with chronic obstructive pulmonary disease. Urgent chemotherapy for lifethreatening complications. Pdf highrisk patients following hospitalisation for an. From october 2006 to june 2007, lung specialists from 68 french general hospitals consecutively included 1,824 patients newly admitted in their respiratory medicine department for an acute exacerbation of copd, regardless of the source of admission i.
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